Veterinary Pharmacology question bank-1

Hello vets , these are some important basic questions regarding veterinary Pharmacology, hope you enjoy it.

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veterinary Pharmacology

Veterinary Pharmacology question bank-1

1. The study of the time course of drug absorption, distribution, metabolism, and excretion is called?
(a) Pharmacodynamic
(b) Drug concentration
(c) Pharmacokinetics
(d) Kinetic homogeneity

 2. The application of pharmacokinetic principles to the safe and effective therapeutic management of drugs in an individual patient is known as?
(a) Pharmacodynamics
(b) Clinical pharmacokinetics
(c) Pharmacology
(d) Pharmacognosy



3. Pharmacodynamics refers to the relationship of drug ?

(a) Dose to drug concentration in plasma
(b) Dose to drug concentration at the receptor site

(c) Concentrations to drug effect
(d) Dose to drug effect



4. Drug pharmacodynamics are affected ?

(a) By the drug concentration at the site of the receptor
(b) Density of receptors on the target cell surface,

(c) Mechanism by which a signal is transmitted into the cell by second messengers
(d) All of the above


5. The EC50 refers to the drug concentration at which?
(a) One-half the maximum response is achieved
(b) The maximal effect is achieved
(c) Tolerance is likely to be observed
(d) All of the above

6. Factors that cause variability in plasma drug concentrations after the same drug dose is given to different patients include variations in the?
(a) Drug absorption
(b) EC50of the drug
(c) LD50 of the drug 

(d) None of the above. 

 7. An example of a situation that would not support therapeutic drug concentration monitoring with plasma drug concentrations would be one in which?

(a) A wide variation in plasma drug concentrations is achieved in different patients given a standard drug dose
(b) The toxic plasma concentration is many times the therapeutic concentration range
(c) Correlation between a drug's plasma concentration and therapeutic response is good
(d) None of the above




8. In pharmacokinetics, the term rate refers to a change in which of the following measurements over time?
(a) Drug dose
(b) Drug elimination
(c) Concentration of drug in plasma
(d) None of the above




9. The most commonly used model in clinical pharmacokinetic situations is the?
(a) One-compartment model
(b) Two-compartment model
(c) Multicompartment model
(d) None of the above


10. Instantaneous distribution to most body tissues and fluids is assumed in which of the following models?
(a) One-compartment model
(b) Two-compartment model

(c) Multicompartment model
(d) None of the above




11. The amount of drug per unit of volume is defined as the?
(a) Volume of distribution

(b) Concentration
(c) Rate
(d) Bioavailability

12. If 3 g of a drug are added and distributed throughout a tank and the resulting concentration is 0.15 g/L, calculate the volume of the tank?

(a) 10 L
(b) 20 L 
(c) 30 L
(d) 200 L

13.For a drug that has first-order elimination and follows a one-compartment model, which of the following plots would result in a curved line?

(a) Plasma concentration versus time
(b) Natural log of plasma concentration versus time
(c) Both
(d) None


14. When pH of a fluid is equal to PKa of a drug the ratio of unionized and ionized form is?

(a) 1:2
(b) 1:4
(c) 2:1
(d) 1:1



15. Metabolism of Codeine to morphine is an example of ?

(a) Pharmacological inactivation
(b) Pharmacological activation
(c) Toxicological activation
(d) No change in activity

• Please Do Comment if you find any error in the answers✅❌

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Answers-

1.C

2.B

3.C

4.D

5.A

6.A

7.B

8.C

9.A

10.A

11.B

12.B

13.A

14.D

15.C